Retatrutide: The Newest Weight Loss Peptide Now Available at Iowa IV

Have you struggled to lose weight and already tried Semaglutide or Trizepatide but failed to lose weight? Don’t give up; the next generation of weight loss peptides is here. At Iowa IV, we are proud to introduce Retatrutide, one of the most promising therapies in weight loss.

But what is Retatrutide, and how does it compare to or differ from the popular weight loss peptides like GLP-1s Semaglutide, Ozempic, and Wegovy or GLP-1/GIPs Tirzepatide, Mounjaro, and Zepbound? Here is what you should know.

What is Retatrutide?

Retatrutide is a medication that activates three hormone systems that help control metabolism and appetite.  GLP-1 receptors help reduce your appetite and slow digestion. This is the same pathway that semaglutide targets. GIP receptors improve how insulin responds and support metabolic balance. This is also how Tirzepatide works. Glucagon is what makes Retatrutide different by enhancing fat burning and increasing energy use. This pathway is only activated by Retatrutide.

Glucagon is what sets this weight loss peptide apart from the others. Glucagon is known for raising blood sugar when glucose levels drop, helping burn more calories, and breaking down stored fat. When combined with the effects of GLP-1 and GIP, they help to make you feel full sooner, stay full longer, and keep blood sugar steady after you eat. This triple combination gives you more complete weight loss support. To keep it simple, GLP-1 and GIP help you to eat less, which stores fewer calories, and glucagon helps you burn more of the stored fat you already have.

In a 48-week clinical trial published in The New England Journal of Medicine, some participants lost up to 24.2 percent of their body weight, which is significantly more than what is typically seen with Semaglutide or Tirzepatide over a similar period (Jastreboff et al., 2023).

‍

How does Retatrutide compare to other weight loss peptides?

‍

Preserve Lean Muscle and Support Natural Growth Hormone Production

‍

What makes Retatrutide even more exciting is its ability to help preserve lean muscle tissue and naturally support growth hormone production, something most people don’t expect from a weight loss medication.

Most weight loss programs lead to both fat and muscle loss, and that’s a problem. When you lose muscle, your metabolism slows down, making it harder to maintain your results long-term. Retatrutide works differently. The glucagon activation not only ramps up fat burning but may also trigger the release of growth hormone while you sleep.

‍

That means you’re not just losing weight. You’re preserving the muscle you’ve worked hard to build and helping your body become more metabolically active while you rest. When combined with strength-based exercise, Retatrutide becomes a powerful tool to improve your body composition. This is not just about shrinking the number on the scale.

Who is Retatrutide For

Retatrutide may be a good fit if you

• Have struggled to lose weight through diet and exercise alone
• Want a modern, science-based medical solution that does not involve surgery
• Have tried Semaglutide or Tirzepatide but did not see the results you were hoping for
• Are ready to follow a structured plan with expert guidance and support

This medication is suitable for adults from all backgrounds who are motivated to improve their health and are looking for long-term, sustainable results.

Our Program

At Iowa IV, we don’t just send you away with medications. We want to ensure long term sustainable weight loss. To ensure this our program is built on accountability, expert support, and the tools to ensure sustainable results. Each client receives personalized guidance from a dedicated registered nurse, monthly FIt3D body scans, and monthly lipo-b and lipo-c injections to help support you during your program.

Certified Nutritionist Support

As part of our commitment to long-term, sustainable results, our peptide program includes access to a certified nutritionist who will help you make more educated nutritional decisions. They will offer sample meal guides, nutrient support, and practical strategies that align with your health goals, empowering you to build lasting habits that help you lose weight and preserve lean muscle mass during and long after you are done with our peptide program.

If you’re ready for a personalized approach, schedule your custom meal plan call

Find Your Custom Plan

We understand that every individual has unique fitness goals and needs, which is why our medical team is dedicated to creating a custom workout plan just for you. After you complete our tailored survey, our team will analyze your responses and design a personalized one-month fitness plan that aligns with your specific requirements. This customized plan will be sent directly to you, ensuring that you have the guidance and support necessary to achieve your health goals and maintain your lean muscle mass. Take the workout survey here.

Fit3D Scanner

All of our peptide programs include free monthly scans in our Fit3D scanner. In an approximately 35-second, non-invasive scan, the Fit3D captures body measurements, body shape scoring, posture analysis, body composition, and more. You will be able to compare your monthly scans to track your progress through the program. It also shows how you compare against healthy ranges and others of the same age and gender. A 3D avatar helps keep you motivated by visually seeing the changes in your body as you work toward your wellness and body-shape goals, giving you more insight than what a scale alone can do.

Ready to Get Started?

If you are looking for long lasting results, Schedule your free consultation today and take the first step toward a healthier, more confident you. From advanced weight loss peptides like Retatrutide to personalized fitness and nutrition support, our team is here to help you reach your goals with confidence. Whether you are just getting started or wanting to take your health to the next level we are here for you every step of the way.

‍

Written by Scott McDonald

Paramedic and Chief Strategic Officer, Clinical Educator at Iowa IV

Reviewed by Jake Sanchez

MSN, FNP-BC, FNP-C, CCRN and Medical Director of Iowa IV

‍